While small-count MBL hardly ever progresses to CLL, higher-depend MBL progresses to CLL demanding therapy in a charge of one% to two% every year. High-depend MBL is distinguished from Rai 0 CLL according to whether or not the B-cell rely is previously mentioned or below five × 109/L. Whilst people with the two large-rely MBL and CLL Rai phase 0 a